Specialty Medicines Market Access Patient Safety
PHARMACOVIGILANCE & PATIENT SAFETY

Pharmacovigilance & Patient Safety

A structured safety system for receiving, documenting, assessing, following up, and appropriately escalating adverse event information associated with our products.

From Safety Signal to Action

Every safety report contributes to the continuous monitoring of the benefit–risk profile of pharmaceutical products.

Report
Receive
Document
Assess
Follow Up
Escalate / Act
OUR PV FRAMEWORK

Our Pharmacovigilance Framework

EndoCare+ operates pharmacovigilance activities through documented procedures, defined responsibilities, controlled reporting channels, and structured case-handling processes. These processes are designed to support the timely identification, documentation, assessment, follow-up, and appropriate escalation of safety information.

Governance

Defined responsibilities and oversight.

SOP-Based Processes

Documented procedures supporting consistent pharmacovigilance activities.

Safety Reporting

Structured channels for receiving adverse event and safety information.

Follow-Up & Escalation

Appropriate follow-up and escalation of cases according to case characteristics and applicable requirements.

SOP-Based Pharmacovigilance Operations

Pharmacovigilance activities are supported by documented Standard Operating Procedures (SOPs) that define relevant responsibilities, reporting pathways, case-handling processes, documentation requirements, follow-up activities, and escalation mechanisms.

Regulatory Alignment

EndoCare+ conducts pharmacovigilance activities with reference to applicable requirements and guidance issued by the relevant pharmaceutical regulatory authorities in Yemen, including the Supreme Board of Drugs and Medical Appliances (SBDMA). Where applicable, international pharmacovigilance principles and recognized safety-reporting practices are incorporated into our operating framework.

Structured Safety Reporting

EndoCare+ uses structured adverse-event reporting formats and information requirements designed to capture the essential elements needed for safety assessment and follow-up. Reporting practices are aligned, where applicable, with relevant local regulatory requirements and internationally recognized pharmacovigilance principles.

INFORMATION COLLECTION

Safety Information Collection

Safety information may be received through multiple channels, including healthcare professionals, patients, caregivers, customers, distributors, company personnel, regulatory authorities, and other relevant sources. Reports are documented and handled through defined pharmacovigilance processes.

Healthcare Professional
Patient / Caregiver
Customer
Company Personnel
Regulatory Authority
Safety Intake
Case Assessment
Follow-Up
Appropriate Action
CASE MANAGEMENT

From Report to Case Management

01

Intake

Receiving safety information.

02

Validation

Reviewing the information available for case handling.

03

Documentation

Recording relevant case details.

04

Assessment

Evaluating the available safety information.

05

Follow-Up

Obtaining additional information where appropriate.

06

Escalation

Escalating cases according to seriousness and procedures.

SERIOUS EVENTS

Serious Events Require Appropriate Escalation

Reports involving serious or potentially serious events receive appropriate attention and escalation according to their characteristics, available information, defined procedures, and applicable regulatory requirements.

Life-threatening
Hospitalization
Disability
Congenital anomaly
Death

Non-serious events and other relevant safety information may also be reported.

Case Follow-Up

Where additional information is necessary and reasonably obtainable, EndoCare+ may conduct follow-up with the reporter or relevant source to clarify case details and support appropriate safety assessment.

Confidentiality & Data Protection

Safety information is handled with appropriate confidentiality and access controls. Personal information is used only for legitimate pharmacovigilance, follow-up, regulatory, and related safety purposes, subject to applicable requirements.

RESPONSIBILITIES

Clear Responsibilities

Pharmacovigilance

Safety intake, case management, follow-up and escalation.

Quality

Product quality complaints, quality investigations and relevant interfaces.

Regulatory Affairs

Regulatory communication and applicable authority interactions.

REPORTING CHANNELS

Safety Event or Product Quality Issue?

Not every product-related report is the same. Suspected adverse events and product quality complaints may require different assessment and handling pathways.

For Urgent Safety Information

For urgent or serious safety information requiring immediate attention, use the designated pharmacovigilance reporting channel.

“Pharmacovigilance is not limited to a reporting form. It is an ongoing safety culture involving awareness, communication, documentation, follow-up, and continuous attention to the benefit–risk balance of medicines.”

Patient Safety Is a Continuous Process

Every safety report helps strengthen the information available to support appropriate decisions and protect patients. EndoCare+ encourages healthcare professionals, patients, caregivers, and other relevant stakeholders to report suspected adverse events and other important safety information.

Report a Safety Event

If you suspect an adverse event related to an EndoCare+ product, please submit a report through our secure channel.

Report a Safety Event